Sriwijaya Journal of Medicine

The Relationship Between The Menstrual Cycle and The Incidence of Acne Vulgaris in Female Students at The Faculty of Medicine, Baiturrahmah University Padang Class of 2022

Sri Handayani — 2024-06-10

Acne vulgaris is a disease that attacks the pilosebaceous unit and can cause non-inflammatory and inflammatory lesions, as well as varying degrees of scarring. In Southeast Asia, the prevalence of acne vulgaris reaches 40-80% of cases. The exact etiology and risk factors for the development of acne vulgaris remain uncertain. However, one factor that is thought to play a role is the fluctuation in estrogen and progesterone that occur during the menstrual cycle in women. This study aimed to determine the relationship between the menstrual cycle and the incidence of acne vulgaris in student at the faculty of medicine, Baiturrahmah University, Padang, class of 2022. The type of research is observational analytics, consist of 48 samples using a consecutive sampling technique. Univariate data analysis is presented and bivariate analysis using the chi-square test. Data processing using the computerized SPSS version 25.0. The highest incidence of acne vulgaris was 75.0% and the highest menstrual cycle was normal was 64.6%. There is relationship between menstrual cycle disorders and the incidence of acne vulgaris (p=0.015) and none the relationship between abnormal menstrual cycles and the incidence of acne vulgaris (p=1.000). There is relationship between menstrual cycle disorders and the incidence of acne vulgaris and there is no relationship between abnormal menstrual cycles and the incidence of acne vulgaris instudent at the Faculty of Medicine, Baiturrahmah University, Padang, Class of 2022.

Genetic Conditions Associated with Intellectual Disability in Indonesian Population: A Review

Ziske Maritska — 2024-06-10

Intellectual disability (ID) brings challenges to the affected individuals, their families, and the community at large. It is a multifactorial condition with many contributing factors, namely genetics. This review aims to briefly provide several related genetic conditions for ID in the Indonesian population. Literature studies search relevant articles using PubMed and Google Scholar using the terms ‘intellectual disability’, ‘genetics', ‘Indonesian population’. In Indonesia, the prevalence of children with ID is 1–3%, with 62,011 school-aged children affected with Intellectual Disability. Genetics plays a role in around 25–50% of cases. ID in the Indonesian population is associated with several genetic disorders, namely Duchenne muscular dystrophy (DMD), autism spectrum disorder (ASD), fragile X syndrome (FXS), Down syndrome (DS), Apert syndrome, and subtelomeric chromosomal rearrangements. There is limited research on genetics related to intellectual disability in Indonesia, implying further research is needed.

Characteristic Analysis of Serum Vitamin D Levels with Hba1c in Type 2-Diabetes Mellitus Patients

Emma Novita — 2024-06-10

Diabetes is one of the most rapidly growing global health emergencies of the 21st century, it is estimated that 537 million (10.3%) people have diabetes, and this number is expected to reach 643 million (11.3%) in 2030, and 783 million (12.2%) %) in 2045. Vitamin D plays a role in insulin secretion by stimulating beta-cell secretion or facilitating the conversion of pro-insulin to insulin. Therefore, vitamin D deficiency may be involved in the pathogenesis of DM type 2. This study aims to analyze the characteristics, HbA1c level status, and vitamin D level status in DM type 2 patients in primary care. The research was conducted in September 2022 with DM type 2 patients who came to the Plaju Palembang Health Center as research subjects. The results showed that there was a significant relationship between age and HbA1c levels in DM type 2 patients (p=0.020) and there was no relationship between gender, occupation, education level, BMI, abdominal circumference, family history, duration of diabetes, and vitamin D levels with HbA1c levels in DM type 2 patients (p>0.05)

Curve Analysis After Bracing in Scoliosis Patients

Rury Tiara Oktariza — 2024-06-10

Bracing is one of the scoliosis treatment methods recommended for patients with a curve of 25° to 40° still growing child or with curves less than 25°. Bracing aims to prevent the progression of curvature. This study aimed to evaluate the decrease in the Cobb angle after a 3-month bracing in scoliosis patients. We retrospectively reviewed the medical records of 67 scoliosis patients for age, gender, and the Cobb angle before and after wearing a brace for 3 months. The data was analyzed using a paired t-test with a confidence level of 95%. The research results showed that scoliosis is predominant in females (76.12%) and at 10-15 years old (60.78%). The mean pre-brace Cobb angle of 24.94° (±7.24) was reduced significantly (P < 0.001) to 16.37° (±7.34). The use of a brace in scoliosis patients, especially teenagers, can correct the curvature of the spine.

Medication Safety as an Effort to Prevent Medication Errors in Midwifery

Nina Zuhana — 2024-06-10

Patient safety is defined as an effort to prevent things that endanger patients in the process of administering drugs. Overall patient safety or prevention and reduction of errors of various risks resulting from such errors. During the process of health services, especially in the treatment of patients, mistakes can be made by health workers. The incidence of Drug Error is a measure of patient safety achievement. The purpose of this study was to analyze the implementation factors of medication safety in an effort to prevent drug errors in obstetrics. The research design chosen is qualitative . This research will be carried out at RSIA Aisyiyah on midwives who work in the inpatient room. Data collection techniques in this study conducted in-depth interviews with 10 informants consisting of midwives in the treatment room. Data analysis is carried out to process qualitative data. Some factors that influence the application of patient safety principles in hospital X include leadership factors, namely lack of supervision from the leadership, lack of human resources for health servants both nurses and pharmacy personnel, workplace environmental factors that are less conducive, unavailability of SPO drug administration with principle 7 correct, socialization that is not carried out consistently and continuously and does not run training or training programs. Some suggestions that may be considered by hospital X in order to provide safe services and in accordance with patient safety principles in drug administration.

Relationship of Hemoglobin and Muscle Strength with Quality of Life in Patients with Chronic Renal Failure

Safitri Nur Rahayu — 2024-06-10

The elderly population is vulnerable to degenerative diseases, one of which is Chronic Kidney Disease (CKD). The age of most hemodialysis patients is between 45 and 54 years. Hemoglobin levels and muscle strength in CKD tend to be low which is associated with a decrease in quality of life in CKD. This research is an observational analytical study with a cross-sectional approach. A total of 24 data points from chronic kidney failure patients at Budhi Asih Regional Hospital, Jakarta, were used in this study. Both primary and secondary data were collected. Hemoglobin levels were obtained from medical records, muscle strength was measured using a Camry handgrip dynamometer, and quality of life was assessed through interviews using the Kidney Disease Quality of Life Short Form questionnaire. Statistical analysis was performed using Fisher's exact test with SPSS 29 for Windows, with a p-value of <0.05. Of the 24 study subjects, 20 (83.3%) had anemia, 17 (70.8%) had low muscle strength, and 9 (37.5%) had a poor quality of life. The study's results showed a significant relationship between hemoglobin levels and both muscle strength and the quality of life of chronic kidney failure sufferers, with p-values of 0.012 and 0.022, respectively. There is a relationship between hemoglobin levels and muscle strength and the quality of life of chronic kidney disease sufferers at Budhi Asih Regional Hospital.

CRISPR-CAS System: Current Applications and Future Prospect

Adinda Adinda — 2024-06-10

The CRISPR-Cas system is a revolutionary technology that has transformed gene editing and has the potential to revolutionize many fields. It is a bacterial immune system that can be programmed to recognize and cleave specific DNA sequences using Cas proteins and guide RNAs. This technology has numerous biotechnological and bioengineering applications and is simpler to design with high targeting efficiency and multiplex editing capability compared to older gene editing technologies. This review aims to explore the general application, impact on molecular biology and medicine, limitations, and future potential of the CRISPR-Cas system. With its potential to revolutionize medicine, agriculture, and environmental science, the CRISPR-Cas system is a powerful gene editing tool that offers hope for a wide range of applications.

Description of the Incidence of Anemia in Young Women at SMPN 2 Depok, Yogyakarta

Dani Ferdian — 2024-06-10

Anemia is an important problem experienced by many teenagers. Anemia is a lack of red blood cells in the body. Young women are more susceptible to anemia, this is related to their own condition of experiencing menstruation (menstruation) and the result of an unhealthy diet. Therefore, further research is needed to describe anemia in adolescent girls. The aim of this study is to describe the incidence of anemia in adolescent girls at SMPN 2 Depok, Yogyakarta. The method used in this research is descriptive study. The sample in this study used total sampling. The sample was 57 8th grade teenage girls at SMPN 2 Depok, Yogyakarta. data analysis using descriptive analysis. As much as 56.14% of the 51 teenage girls who took part in the activity had anemia or anemia (32 teenage girls). This shows that the incidence of anemia among adolescent girls at SMPN 2 Depok is still high. One of the causes of anemia in adolescent girls is the lack of prevention of anemia in adolescent girls, such as taking blood supplement tablets and consuming foods with balanced nutrition. The incidence of anemia in adolescent girls is still high, so efforts are needed to prevent anemia by schools collaborating with nearby health facilities.

Comparison of Germ Patterns between Cholesteatom Tissue and Tympanic Cavum Mucosa Tissue in COSM with Cholesteatom at Dr. Mohammad Hoesin Hospital, Palembang

Resti Ramdani — 2024-06-10

Chronic Suppurative Otitis Media (CSOM) is middle ear inflammation due to infection characterized by otorrhea through perforation of the tympanic membrane that occurs for more than three months. Identifying bacterial patterns in CSOM is essential for managing CSOM patients with cholesteatoma. Proper administration of antibiotics is crucial to overcome infection and prevent widespread resistance. To compare the germ patterns between cholesteatoma tissue and tympanic cavum mucosal tissue in CSOM patients with cholesteatoma. This observational study has a cross-sectional design, and data collection was carried out using primary data taken from 27 CSOM patients with cholesteatoma who underwent mastoidectomy surgery with a total of 54 research samples taken from the examination of cholesteatoma tissue swabs and tympanic cavum mucosal tissue from August to October 2023. From the reliability coefficient between the two tissues using the Cohen's Kappa technique, there is a significant concordance in the germ pattern between the tympanic cavum mucosa tissue and the tympanic cavum mucosa of 0.580 (Moderate) p<0.005, with Pseudomonas aeruginosa, Proteus mirabilis and Klebsiella pneumoniae with a significance value of 0.656 (Good) p<0.001. There is a significant concordance in the germ pattern between cholesteatoma tissue and tympanic cavum mucosa tissue in CSOM cases with cholesteatoma. The most common bacteria in both tissues are Gram-negative, namely Pseudomonas aeruginosa, proteus mirabilis, and Klebsiella pneumoniae.

The Relationship Between The Level of Knowledge and The Way of Handling Burns In Employees of The Fire Department of Palembang City

Qonitah Muhsinah — 2024-06-10

Burns are injuries characterized by damage to skin tissue due to direct contact with a source that conducts heat. Some action activities that have a high risk of burns are firefighters. This reflects that the level of knowledge and handling of burns is very important and becomes the main focus as a firefighter. This study aims to determine the relationship between the level of knowledge and how to handle burns on fire department employees in Palembang. This study was an observational analytic study with a case series approach. with a sample of Fire Department Employees in Palembang. The data used is primary data derived from questionnaires. Researchers recorded data such as age, gender, education, level of knowledge of burns, and knowledge of how to treat burns. 180 people met the research criteria. The dominating characteristics were age 26-35 years (58.3%), male (81.7%), female (18.3%), the level of knowledge about burns was in the good category (40.5%). And knowledge of how to handle burns is in the good category (61.7%). Analysis using bivariate analysis found that there was a significant correlation between the level of knowledge and how to handle burns (p=0.000; r=0.452). Most respondents in this study were aged 26-35 years, male and had a Diploma / Bachelor's degree. The level of knowledge about burns and how to handle them was mostly in the good category. In the correlation test, there was a significant correlation between the level of knowledge and how to handle burns.