Sriwijaya Journal of Medicine

Identification of Type 2 Diabetes Mellitus Risk Factors in Urban Communities Of Archipelago and Mining Regions: Stakeholders Perspective

Kamalia Layal, Restu Amalia Azmy, Zulkifli, Suherman — Mon, 16 Jun 2025 00:00:00 +0000

Bangka Belitung is an archipelagic region and the world's second-largest tin producer. Communities in coastal and mining areas face health issues related to behavior, individual characteristics, and cultural factors influencing disease patterns. One prevalent disease among urban populations in Bangka Belitung is diabetes mellitus. This study aims to explore the risk factors of diabetes mellitus in urban communities in Bangka Belitung from the stakeholders' perspective. This research employed a qualitative exploratory approach conducted in Pangkalpinang city. Data were collected through in-depth interviews with participants, including eight heads of public health centers, one head of the health department, one chairperson of the Indonesian Medical Association (IDI), nine patients, and nine family members of patients across nine public health center service areas in Pangkalpinang city. Data were analyzed using thematic analysis. The study identified three main themes: (1) Lifestyle, (2) Social, economic, and environmental factors, and (3) Cognitive psychology. These factors contribute to the high prevalence of type 2 diabetes mellitus (T2DM) in urban communities in the Bangka Belitung archipelago. Comprehensive knowledge and understanding of T2DM are essential to implement effective prevention and intervention strategies to control T2DM cases in urban communities in this archipelagic and mining region.

Systematic Review: Antifungal Efficacy of Morinda Citrifolia Against Candida Albicans

Intan Purnama, Susilawati, Gita Dwi Prasasty — Sun, 22 Jun 2025 00:00:00 +0000

Candidiasis, caused by Candida species, remains a significant global health concern, with oral and vulvovaginal forms prevalent among immunocompromised populations and women, respectively. Increasing antifungal resistance, particularly among non-albicans species, underscores the need for novel therapeutic options. This systematic literature review assesses the antifungal efficacy of Morinda citrifolia (noni fruit) against Candida albicans. Utilizing the PRISMA protocol, we analyzed studies from Scopus, ScienceDirect, PubMed, and Google Scholar databases published between 2014 and 2024. Seven in vitro studies were included, examining the inhibitory effects of M. citrifolia extracts on C. albicans. Findings indicate that M. citrifolia exhibits significant antifungal properties, attributed to its bioactive compounds such as scopoletin and flavonoids, which disrupt fungal cell membranes. The effectiveness of M. citrifolia is concentration-dependent, with higher concentrations yielding greater antifungal activity. Given the increasing resistance to conventional antifungals, in vitro studies suggest that M. citrifolia may be a promising alternative, warranting further in vivo and clinical investigations to substantiate its therapeutic potential.

Non-Hormonal Pharmacological Interventions to Manage Vasomotor Symptoms During Menopause

Gilang Amanda Hambali, Adnan Abadi — Fri, 27 Jun 2025 00:00:00 +0000

This study reviews a range of non-hormonal pharmacological interventions used to treat vasomotor symptoms in postmenopausal women, including SSRIs, SNRIs, gabapentin, and neurokinin-3 receptor (NK3R) antagonists. Methods used included a literature review of multiple clinical trials and meta-analyses published over the past decade. Results showed that all interventions were effective in reducing the frequency and severity of hot flashes, with efficacy rates ranging from 36 to 72%. In addition, the side effect profile was generally mild to moderate, including nausea, sleep disturbance, and headache. NK3R antagonists, such as fezolinetant, have shown great promise with a rapid onset of action and comparable efficacy to hormone therapy, but longer-term studies are needed to assess safety. This study emphasizes the importance of an individualized approach to therapy selection and the need for monitoring liver function and potential side effects. Conclusions suggest that these non-hormonal interventions are a promising alternative for postmenopausal women for whom hormone therapy is contraindicated.

The Level of Knowledge as a Predictor of Husband’s Participation in Vasectomy: A Study at Buleleng I Community Health Center, 2023

Luh Yenny Armayanti, Ketut Sri Mentari, Putu Rama Pratama Karma — Sat, 28 Jun 2025 00:00:00 +0000

Male participation in Family Planning (FP) programs, particularly in permanent contraceptive methods such as vasectomy, remains significantly low in Indonesia. This study aimed to examine the relationship between the level of husband’s knowledge and their participation in vasectomy use within the working area of Buleleng I Public Health Center in 2023. Purposive sampling was used to choose 76 male respondents of reproductive age who were already parents in a cross-sectional, quantitative analytical study. A systematic questionnaire addressing two main variables knowledge of vasectomy and involvement in its use was used to gather data. Both univariate and bivariate techniques were used to analyze the data, and Pearson's correlation test was used to look at how the variables related to one another. A mean score of 80.80 (SD ±10.05) indicated that respondents had a high level of knowledge, whereas a mean score of 4.63 (SD ±0.72) indicated moderate participation in the vasectomy program. Knowledge and participation were shown to be significantly correlated by the correlation analysis (p = 0.001). These findings suggest that a husband's propensity to use vasectomy as a form of contraception increases with his degree of understanding. This study comes to the conclusion that one of the main factors influencing men's participation in vasectomy is knowledge. Therefore, community-based educational interventions and health promotion initiatives should be strengthened to enhance men’s awareness and involvement in family planning programs, as part of broader efforts to promote gender equity in reproductive health.

Overweight Is Related To Seborrheic Dermatitis Condition In The Adult Population

Nyai Oktika Dagis, Patwa Amani — Mon, 30 Jun 2025 00:00:00 +0000

Seborrheic Dermatitis (SD) is a common skin condition characterized by papulosquamous lesions, often occurring on the scalp, face, and other areas rich in sebaceous glands. While not life-threatening or contagious, SD can have a significant psychological impact due to the social stigma associated with poor hygiene, especially in the adult population. This study aimed to analyze the relationship between body mass index (BMI) and the incidence of SD in the adult population. The research was conducted with a cross-sectional observational approach. Data were collected by reviewing medical records and then analyzed using the chi-square test. A total of 126 samples were involved in this study, consisting of 44 men (66.7%) and 39 women (65.0%), ranging from 26-45 years old. Our study resulted in a significant relation between BMI and the incidence of SD (p = 0.004).

Retrospective Study: Serum Hemoglobin, Erythrocyte, and Creatinine Profiles of Chronic Kidney Disease Patients After Hemodialysis

Mely Purnadianti, Selviani Muhtadi — Mon, 30 Jun 2025 00:00:00 +0000

Chronic kidney disease (CKD) is a pathological process with various etiologies, causing a progressive and irreversible decline in kidney function. Hemodialysis is used to remove certain metabolic waste or toxins. The purpose of this study was to analyze the relationship between hemoglobin levels, erythrocyte count, and creatinine levels in chronic kidneys after undergoing hemodialysis. The research design used was Cross Sectional with an analytical observational method. In this study, there were 25 respondents who were taken using the Purposive Sampling technique. The data analysis used was the normalization test using the Pearson Test. Based on the Pearson Correlation test between Hemoglobin Levels, Erythrocyte Counts, and Creatinine Levels in patients with chronic kidney disease after undergoing hemodialysis, the results were obtained with a correlation coefficient value of 0.932 which means that the correlation strength is very strong. As for the sig value. 0.000 (<0.05) there was an association between Hemoglobin Level and Erythrocyte Number in patients with chronic kidney disease. The value of the correlation coefficient is 0.099 As for the value of sig. 0.636 (>0.05) indicates that there is no association between Hemoglobin Levels and Creatinine Levels in patients with chronic kidney disease. The conclusion was that there was a relationship between Hemoglobin levels and Erythrocyte Count in patients with chronic kidney disease at Gambiran Hospital, but there was no relationship between Hemoglobin levels and Creatinine levels in patients with chronic kidney disease in patients with chronic kidney disease and there was no association between the number of erythrocytes and creatinine levels in patients with chronic kidney disease at Gambiran Hospital