Identification of Type 2 Diabetes Mellitus Risk Factors in Urban Communities Of Archipelago and Mining Regions: Stakeholders Perspective

Kamalia Layal, Restu Amalia Azmy, Zulkifli, Suherman — Mon, 16 Jun 2025 00:00:00 +0000

Bangka Belitung is an archipelagic region and the world's second-largest tin producer. Communities in coastal and mining areas face health issues related to behavior, individual characteristics, and cultural factors influencing disease patterns. One prevalent disease among urban populations in Bangka Belitung is diabetes mellitus. This study aims to explore the risk factors of diabetes mellitus in urban communities in Bangka Belitung from the stakeholders' perspective. This research employed a qualitative exploratory approach conducted in Pangkalpinang city. Data were collected through in-depth interviews with participants, including eight heads of public health centers, one head of the health department, one chairperson of the Indonesian Medical Association (IDI), nine patients, and nine family members of patients across nine public health center service areas in Pangkalpinang city. Data were analyzed using thematic analysis. The study identified three main themes: (1) Lifestyle, (2) Social, economic, and environmental factors, and (3) Cognitive psychology. These factors contribute to the high prevalence of type 2 diabetes mellitus (T2DM) in urban communities in the Bangka Belitung archipelago. Comprehensive knowledge and understanding of T2DM are essential to implement effective prevention and intervention strategies to control T2DM cases in urban communities in this archipelagic and mining region.

Systematic Review: Antifungal Efficacy of Morinda Citrifolia Against Candida Albicans

Intan Purnama, Susilawati, Gita Dwi Prasasty — Sun, 22 Jun 2025 00:00:00 +0000

Candidiasis, caused by Candida species, remains a significant global health concern, with oral and vulvovaginal forms prevalent among immunocompromised populations and women, respectively. Increasing antifungal resistance, particularly among non-albicans species, underscores the need for novel therapeutic options. This systematic literature review assesses the antifungal efficacy of Morinda citrifolia (noni fruit) against Candida albicans. Utilizing the PRISMA protocol, we analyzed studies from Scopus, ScienceDirect, PubMed, and Google Scholar databases published between 2014 and 2024. Seven in vitro studies were included, examining the inhibitory effects of M. citrifolia extracts on C. albicans. Findings indicate that M. citrifolia exhibits significant antifungal properties, attributed to its bioactive compounds such as scopoletin and flavonoids, which disrupt fungal cell membranes. The effectiveness of M. citrifolia is concentration-dependent, with higher concentrations yielding greater antifungal activity. Given the increasing resistance to conventional antifungals, in vitro studies suggest that M. citrifolia may be a promising alternative, warranting further in vivo and clinical investigations to substantiate its therapeutic potential.

Sriwijaya Journal of Medicine

Identification of Type 2 Diabetes Mellitus Risk Factors in Urban Communities Of Archipelago and Mining Regions: Stakeholders Perspective

Systematic Review: Antifungal Efficacy of Morinda Citrifolia Against Candida Albicans